DMT-dU-CE Phosphoramidite 2'-O-MOE Phosphoramidites The 2'-OMe modification improves duplex

The 2'-OMe modification improves duplex stability

and applications of oligonucleotides containing an RNA dinucleotide phosphorothiolate linkage

a 5’-dimethoxytrityl (DMT) protecting group for 5’-hydroxyl protection

Flexible Scale

[2] Dowler

DMT-dU-CE Phosphoramidite 2'-O-MOE Phosphoramidites The 2'-OMe modification improves duplexDMT dU CE Phosphoramidite is a standard DNA phosphoramidite monomer used for solid phase oligonucleotide synthesis[1][2]. It contains a 5 dimethoxytrityl (DMT) protecting group for 5 hydroxyl protection, a cyanoethyl (CE) protecting group on phosphite, and a uracil. This phosphoramidite enables the incorporation of deoxyuridine (dU) residues into synthetic DNA containing oligonucleotides with high coupling efficiency and sequence fidelity.