Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4)-Exatecan Size:25mg Product Name BG-DOTA-tris(t-Bu) Synonyms SNAP-DOTA-tris(t-Bu)

Product Name BG-DOTA-tris(t-Bu) Synonyms SNAP-DOTA-tris(t-Bu) CAS Number n/a Related CAS Molecular Formula C41H64N10O8 Molecular Weight 825

404 SMILES CN1C(=O)C(C)=C2N(C(=O)N(C3CC3)C(=O)C2=C1NC1=C(F)C=C(I)C=C1)C1=CC(NC(C)=O)=CC=C1 Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO

Indisulam promotes the recruitment of RBM39 (RNA binding motif protein 39) to the CUL4-DCAF15 E3 ubiquitin ligase

S)-AHPC-CO-PEG6-OH Synonyms CAS Number n/a Related CAS Molecular Formula C35H54N4O10S Molecular Weight 722

- CAS Number: 2307477-23-0 Molecular Formula: C18H22ClN3O5 Molecular Weight: 395

Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4)-Exatecan Size:25mg Product Name BG-DOTA-tris(t-Bu) Synonyms SNAP-DOTA-tris(t-Bu)SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by