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Mal-Propionyl-PEG6-Gly-Gly-Phe-Gly-PAB(m-PEG4) mmae which readily reacts with an

SKU: 12914069975

4.8
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Description

which readily reacts with an alkyne via click chemistry

DOTA bifucational chelator containing an amine group

5(6)-FAM PEG3 azide is an excellent alkyne-reactive fluorescent reagent for labeling alkyne-containing biological molecules through click chemistry

054 SMILES [2H]C([2H])([2H])OC1=CC=C(Br)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Bioconjugate Chemistry

Mal-Propionyl-PEG6-Gly-Gly-Phe-Gly-PAB(m-PEG4) mmae which readily reacts with anSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG6 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker

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